| Design, Synthesis and Biological Evaluation of NovelConformationally Constrained Inhibitors Targeting Epidermal Growth Factor Receptor T790M mutant |
Shaohua Chang, Lianwen Zhang, Shilin Xu, Jinfeng Luo, Xiaoyun Lu, Zhang Zhang, Tianfeng Xu, Yingxue Liu, Zhengchao Tu, Yong Xu, Xiaomei Ren, Meiyu Geng, Jian Ding, Duanqing Pei and Ke Ding |
2012 |
J. Med. Chem |
| Direct Carboxamidation of Indoles by Palladium-catalyzed C-H Activation and Isocyanide Insertion |
Jiangling Peng, Lanying Liu, Ziwei Hu, Jinbo Huang and Qiang Zhu |
2012 |
Chem. Commun |
| Palladium-Catalyzed Amidation of N-Tosylhydrazones with Isocyanides |
Zhou, Fengtao; Ding, Ke; Cai, Qian. |
2011 |
Chem. |
| Identification of pyrido[1,2-a]pyrimidine-4-ones as new mole-cules Improving the transcriptional functions of estrogen-related receptor. |
Lijie Peng, Xuefei Gao, Duan Lei, Xiaomei Ren, Donghai Wu, Ke Ding. |
2011-11-10 |
Journal of Medicinal Chemistry |
| A Concise Total Synthesis of (±) Minfiensine.Org Lett. |
Peijun Liu, Juan Wang, Jiancun Zhang, Fayang G Qiu. |
2011-12-16 |
Org Lett. |
| The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner. |
Tao Wang, Keshi Chen, Xiaoming Zeng, Jianguo Yang, Yun Wu, Xi Shi, Baoming Qin, Lingwen Zeng, Miguel Angel Esteban, Guangjin Pan and Duanqing Pei. |
2011-12-02 |
Cell Stem Cell |
| Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element. |
J Xu, B Wang, Y Xu, L Sun, W Tian, D Shukla, R Barod, J Grillari, R Grillari-Voglauer, PH Maxwell and MA Esteban |
2011-08-15 |
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| Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning |
Dongshan Yang, Huaqiang Yang, Wei Li, Bentian Zhao, Zhen Ouyang, Zhaoming Liu, Yu Zhao, Nana Fan, Jun Song, Jiangtian Tian, Feng Li, Jifeng Zhang, Lin Chang, Duanqing Pei, Y Eugene Chen, Liangxue Lai. |
2011 |
Cell Res |
| Hepatocyte nuclear factor-4 alpha regulates liver triglyceride metabolism in part through secreted phospholipase A2 GXIIB |
Min Guan, Linbing Qu, Wenjuan Tan, Ling Chen, Chi-Wai Wong |
2011 |
Hepatology |
| Br？nsted Acid-Promoted Sequential Hydroarylation– Hydroamidation of Arene-Tethered 1-(2-Alkynylphenyl)ureas: Direct Access to 4,4-Spiro-3,4-dihydro-2-(1H)-quinazolinones |
Honggen Wang, Jiaji Zhao, Jiancun Zhang, Qiang Zhu |
2011 |
Advanced Synthesis & Catalysis |
| Generation of induced pluripotent stem cells from urine |
Ting Zhou, Christina Benda, Sarah Duzinger, Yinghua Huang, Xingyan Li, Yanhua Li, Xiangpeng Guo, Guokun Cao, Shen Chen, Lili Hao, Yau-Chi Chan, Kwong-Man Ng, Jenny Cy Ho, Matthias Wieser, Jiayan Wu, Heinz Redl, Hung-Fat Tse, Johannes Grillari, Regina Grillari-Voglauer, Duanqing Pei, Miguel A Esteban |
2011 |
J Am Soc Nephrol |
| Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin |
Shiqiang Zhang, Shen Chen, Wen Li, Xiangpeng Guo, Ping Zhao, Jianyong Xu, Yan Chen, Qiong Pan, Xiaorong Liu, Daniela Zychlinski, Hai Lu, Micky D Tortorella, Axel Schambach, Yan Wang, Duanqing Pei, Miguel A Esteban. |
2011-08-15 |
Hum Mol Genet |
| Reprogramming of mouse and human somatic cells by high-performance engineered factors |
Yang Wang, Jiekai Chen, Jia-Lei Hu, Xi-Xiao Wei, Dajiang Qin, Juan Gao, Lei Zhang, Jing Jiang, Jin-Song Li, Jing Liu, Ke-Yu Lai, Xia Kuang, Jian Zhang, Duanqing Pei, Guo-Liang Xu |
2011-04-01 |
EMBO Rep |
| Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics |
Jiekai Chen, Jing Liu, You Chen, Jiaqi Yang, Jing Chen, He Liu, Xiangjie Zhao, Kunlun Mo, Hong Song, Lin Guo, Shilong Chu, Deping Wang, Ke Ding and Duanqing Pei |
2011 |
Cell Res |
| MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells |
Shipeng Feng, Shujie Cong, Xin Zhang, Xichen Bao, Wei Wang, Huiping Li, Zhe Wang, Guoxin Wang, Jianzhen Xu, Bowen Du, Dezhong Qu, Wei Xiong, Menghui Yin, Xiaoshuai Ren, Feifei Wang, Jianxing He, Biliang Zhang |
2011 |
Nucleic Acids Res |
| A lateral flow biosensor for rapid detection of DNA-binding protein c-jun |
Zhiyuan Fang, Chenchen Ge, Wenjuan Zhang, Puchang Lie, Lingwen Zeng |
2011-09-15 |
Biosens Bioelectron |
| MicroRNA Cluster 302-367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition |
Baojian Liao, Xichen Bao, Longqi Liu, Shipeng Feng, Athanasios Zovoilis, Wenbo Liu, Yanting Xue, Jie Cai, Xiangpeng Guo, Baoming Qin, Ruosi Zhang, Jiayan Wu, Liangxue Lai, Maikun Teng, Liwen Niu, Biliang Zhang, Miguel A Esteban, Duanqing Pei |
2011-05-13 |
J Biol Chem |
| New Ligands That Promote Cross-Coupling Reactions between Aryl Halides and Unactivated Arenes |
Yatao Qiu, Yanghan Liu, Kai Yang, Wenkun Hong, Zheng Li, Zhaoyang Wang, Zhiyi Yao, Sheng Jiang. |
2011-07-15 |
Org Lett |
| Highly Efficient Synthesis of Phenols by Copper-Catalyzed Hydroxylation of Aryl Iodides, Bromides, and Chlorides |
Kai Yang, Zheng Li, Zhaoyang Wang, Zhiyi Yao, Sheng Jiang |
2011-08-19 |
Org Lett |
| Palladium-Catalyzed Intramolecular C(sp(2))-H Amidination by Isonitrile Insertion Provides Direct Access to 4-Aminoquinazolines from N-Arylamidines |
Yong Wang, Honggen Wang, Jiangling Peng, and Qiang Zhu |
2011-09-02 |
Org. Lett |
| Copper-Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl-Substituted Aromatic N-Heterocycles |
Honggen Wang, Yong Wang, Dongdong Liang, Lanying Liu, Jiancun Zhang, Qiang Zhu. |
2011-06-14 |
Angew Chem Int Ed Engl |
| Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase |
Xuefei Gao, Kuai Li, Xiaoyan Hui, Xiangping Kong, Gary Sweeney, Yu Wang, Aimin Xu, Maikun Teng, Pentao Liu, Donghai Wu |
2011-05-01 |
Biochem J |
| BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone. |
Jiekai Chen1, *, Jing Liu1, *, Jiaqi Yang1, You Chen1, Jing Chen1, Su Ni1, Hong Song1, Lingwen Zeng1, Ke Ding1,Duanqing Pei. |
2011 |
Cell Research |
| Copper-Catalyzed Tandem Reactions of 1-(2-Iodoary) -2-yn-1-ones with Isocyanides for the Synthesis of 4-Oxo-indeno[1,2-b]pyrroles |
cai, Qian; Zhou, Fengtao; Xu, Tianfeng; fu, liangbing; Ding, Ke* |
2011-01-21 |
Organic. Letters |
| Phosphatidylinositol 3-kinase affects mitochondrial function in part through inducing peroxisome proliferator-activated receptor γ coactivator-1β expression |
Gao M, Wang J, Wang W, Liu J, Wong CW. |
2011 |
British Journal of Pharmacology |
| A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts |
Li R, Liang J, Ni S, Zhou T, Qing X, Li H, He W, Chen J, Li F, Zhuang Q, Qin B, Xu J, Li W, Yang J, Gan Y, Qin D, Feng S, Song H, Yang D, Zhang B, Zeng L, Lai L, Esteban MA, Pei D |
2010 |
Cell Stem Cell |
| A Direct Intramolecular C-H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles from N-Aryl-2-aminopyridines |
Wang H, Wang Y, Peng C, Zhang J, Zhu Q. |
2010 |
J Am Chem Soc. |
| VHL Inactivation Induces HEF1 and Aurora Kinase A. |
Jianyong Xu*, Huapeng Li*, Bo Wang*, Yan Xu*, Jiayin Yang*, Xiaofei Zhang*, Sarah K. Harten？, Deepa Shukla？, Patrick H. Maxwell？, Duanqing Pei* and Miguel A. Esteban* |
2010 |
J Am Soc Nephrol |
| Expression of Huntington’s disease protein results in apoptotic neurons in the brains of cloned transgenic pigs |
Dongshan Yang1, Chuan-En Wang2, Bentian Zhao1, Wei Li1, Zhen Ouyang1, Zhaoming Liu1, Huaqiang Yang1, Pei Fan3, Ashley O'Neill2, Weiwang Gu3, Hong Yi4, Shihua Li2, Liangxue Lai1,* and Xiao-Jiang Li2,* |
2010 |
Hum. Mol. Genet. |
| Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity |
Zhiyuan Fang, Jing Huang, Puchang Lie, Zhuo Xiao, Chuanyan Ouyang, Qing Wu, Yixing Wu, Guodong Liu and Lingwen Zeng |
2010 |
Chem Commun |
